Mechanism of Diastolic Stiffening of the Failing Myocardium and Its Prevention by Angiotensin Receptor and Calcium Channel Blockers

OBJECTIVE: To investigate the mechanism responsible for the increased cardiac stiffness associated with hypertensive heart failure in Dahl salt-sensitive (DS) rats and the effects of treatment with the combination of a calcium channel blocker [azelnidipine (AZE)] and angiotensin II type 1 receptor b...

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Detalhes bibliográficos
Main Authors: Cheng, Xian Wu, Okumura, Kenji, Kuzuya, Masafumi, Jin, Zhehu, Nagata, Kohzo, Obata, Koji, Inoue, Aiko, Hirashiki, Akihiro, Takeshita, Kyosuke, Unno, Kazumasa, Harada, Ken, Shi, Guo-Ping, Yokota, Mitsuhiro, Murohara, Toyoaki
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904684/
https://ncbi.nlm.nih.gov/pubmed/19528815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e3181ab371d
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