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Th2 cytokines associated with chronic rhinosinusitis with polyps down-regulate the antimicrobial immune function of human sinonasal epithelial cells

BACKGROUND: Chronic rhinosinusitis with nasal polyps (CRSwNPs) is a disorder characterized by persistent eosinophilic Th2 inflammation and frequent sinonasal microbial colonization. It has been postulated that an abnormal mucosal immune response underlies disease pathogenesis. The relationship betwe...

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Autors principals: Ramanathan, Murugappan, Lee, Won-Kyung, Spannhake, Ernst W., Lane, Andrew P.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904676/
https://ncbi.nlm.nih.gov/pubmed/18416964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2500/ajr.2008.22.3136
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