Endothelial nitric oxide synthase activity is inhibited by the plasma membrane calcium ATPase in human endothelial cells

AIMS: Nitric oxide (NO) plays a pivotal role in the regulation of cardiovascular physiology. Endothelial NO is mainly produced by the endothelial nitric oxide synthase (eNOS) enzyme. eNOS enzymatic activity is regulated at several levels, including Ca(2+)/calmodulin binding and the interaction of eN...

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Detalhes bibliográficos
Main Authors: Holton, MaryLouisa, Mohamed, Tamer M.A., Oceandy, Delvac, Wang, Weiguang, Lamas, Santiago, Emerson, Michael, Neyses, Ludwig, Armesilla, Angel L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904661/
https://ncbi.nlm.nih.gov/pubmed/20211863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq077
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