The plasma membrane calcium ATPase 4 signalling in cardiac fibroblasts mediates cardiomyocyte hypertrophy

The heart responds to pathological overload through myocyte hypertrophy. Here we show that this response is regulated by cardiac fibroblasts via a paracrine mechanism involving plasma membrane calcium ATPase 4 (PMCA4). Pmca4 deletion in mice, both systemically and specifically in fibroblasts, reduce...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Mohamed, Tamer M. A., Abou-Leisa, Riham, Stafford, Nicholas, Maqsood, Arfa, Zi, Min, Prehar, Sukhpal, Baudoin-Stanley, Florence, Wang, Xin, Neyses, Ludwig, Cartwright, Elizabeth J., Oceandy, Delvac
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820544/
https://ncbi.nlm.nih.gov/pubmed/27020607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11074
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados