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Obesity and Hyperinsulinemia in a Family with Pancreatic Agenesis and MODY Due to the IPF1 Mutation Pro63fsX60

We studied the genetic and clinical features of diabetic subjects in a five-generation Michigan-Kentucky pedigree ascertained through a proband with pancreatic agenesis and homozygous for the IPF1 mutation Pro63fsx60. Diabetic and nondiabetic family members were genotyped and phenotyped. We also car...

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Détails bibliographiques
Auteurs principaux: Fajans, Stefan S., Bell, Graeme I., Paz, Veronica P., Below, Jennifer E., Cox, Nancy J., Martin, Catherine, Thomas, Inas H., Chen, Ming
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904650/
https://ncbi.nlm.nih.gov/pubmed/20621032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2010.03.003
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