Pregnancy-Associated Plasma Protein-A Increases Osteoblast Proliferation in Vitro and Bone Formation in Vivo

Pregnancy-associated plasma protein (PAPP)-A, a protease for IGF binding protein (IGFBP)-2, -4, and -5, may enhance IGF action by increasing its bioavailability. Here we have determined the role and mechanism of action of PAPP-A in the regulation of osteoblast proliferation in vitro and bone metabol...

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Hauptverfasser: Qin, Xuezhong, Wergedal, Jon E., Rehage, Mark, Tran, Kiet, Newton, Jacqueline, Lam, Paggie, Baylink, David J., Mohan, Subburaman
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904517/
https://ncbi.nlm.nih.gov/pubmed/16946002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2006-1055
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