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Nicotine Blocks Brain Estrogen Synthase (Aromatase): In Vivo Positron Emission Tomography Studies in Female Baboons

BACKGROUND: Cigarette smoking and nicotine have complex effects on human physiology and behavior, including some effects similar to those elicited by inhibition of aromatase, the last enzyme in estrogen biosynthesis. We report the first in vivo primate study to determine whether there is a direct ef...

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Autori principali: Biegon, Anat, Kim, Sung-Won, Logan, Jean, Hooker, Jacob M., Muench, Lisa, Fowler, Joanna S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904480/
https://ncbi.nlm.nih.gov/pubmed/20188349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2010.01.004
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