Epidermal growth factor inhibits intestinal NHE8 expression via reducing its basal transcription

Sodium/hydrogen exchangers (NHEs) play a major role in Na(+) absorption, cell volume regulation, and intracellular pH regulation. Of the nine identified mammalian NHEs, three (NHE2, NHE3, and NHE8) are localized on the apical membrane of epithelial cells in the small intestine and the kidney. Althou...

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Detalhes bibliográficos
Main Authors: Xu, Hua, Zhang, Bo, Li, Jing, Chen, Huacong, Tooley, James, Ghishan, Fayez K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Membrane Transporters, Ion Channels and Pumps
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904261/
https://ncbi.nlm.nih.gov/pubmed/20375273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00081.2010
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