Tumor necrosis factor-α downregulates intestinal NHE8 expression by reducing basal promoter activity

NHE8 transporter is a member of the sodium/hydrogen exchanger (NHE) family. This transporter protein is expressed at the apical membrane of epithelial cells of kidney and intestine and contributes to vectorial Na(+) transport in both tissues. Although NaCl absorption has been shown to be reduced in...

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Bibliografiske detaljer
Main Authors: Xu, Hua, Chen, Huacong, Dong, Jiali, Li, Jing, Chen, Rongji, Uno, Jennifer K., Ghishan, Fayez K.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2009
Fag:
Membrane Transporters, Ion Channels, and Pumps
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660270/
https://ncbi.nlm.nih.gov/pubmed/19109523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00482.2008
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