Fetal growth restriction alters transcription factor binding and epigenetic mechanisms of renal 11β-hydroxysteroid dehydrogenase type 2 in a sex-specific manner

Intrauterine growth restriction (IUGR) increases the risk of serious adult morbidities such as hypertension. In an IUGR rat model of hypertension, we reported a persistent decrease in kidney 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) mRNA and protein levels from birth through postnatal (P) d...

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Detalhes bibliográficos
Main Authors: Baserga, Mariana, Kaur, Rajwinderjit, Hale, Merica A., Bares, Allyson, Yu, Xing, Callaway, Christopher W., McKnight, Robert A., Lane, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904157/
https://ncbi.nlm.nih.gov/pubmed/20427719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00122.2010
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