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Comparison of selective M(3) and nonselective muscarinic receptor antagonists on gastrointestinal transit and bowel habits in humans

Although in vitro studies show that muscarinic M(3) receptors primarily mediate the effects of acetylcholine on gastrointestinal contractility, the muscarinic receptor subtypes regulating gastrointestinal motor activity and transit in humans in vivo are unclear. We hypothesized that muscarinic M(3)-...

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Detalhes bibliográficos
Main Authors: Bharucha, Adil E., Ravi, Karthik, Zinsmeister, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904119/
https://ncbi.nlm.nih.gov/pubmed/20395537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00072.2010
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