Enhancing the Delivery of Anti Retroviral Drug “Saquinavir” Across the Blood Brain Barrier Using Nanoparticles

Antiretroviral drugs are ineffective at treating viral infection in the brain because they cannot freely diffuse across the blood-brain barrier (BBB). Therefore, HIV-1 viral replication persists in the central nervous system (CNS) and continues to augment the neuropathogenesis process. Nanotechnolog...

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Main Authors: Mahajan, Supriya D., Roy, Indrajit, Xu, GaiXia, Yong, Ken-Tye, Ding, Hong, Aalinkeel, Ravikumar, Reynolds, Jessica L., Sykes, Donald E., Nair, Bindukumar B., Lin, Elaine Y., Prasad, Paras N., Schwartz, Stanley A.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904057/
https://ncbi.nlm.nih.gov/pubmed/20426757
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