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Methamphetamine alters blood brain barrier permeability via the modulation of tight junction expression: Implication for HIV-1 neuropathogenesis in the context of drug abuse

The pathogenesis of human immunodeficiency virus (HIV) associated encephalopathy is attributed to infiltration of the central nervous system (CNS) by HIV-1 infected mononuclear cells that transmigrate across the blood brain barrier (BBB). The endothelial tight junctions (TJ) of the blood brain barri...

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Detalhes bibliográficos
Main Authors: Mahajan, Supriya D., Aalinkeel, Ravikumar, Sykes, Donald E., Reynolds, Jessica L., Bindukumar, B., Adal, Adaffaras, Qi, Mingshen, Toh, Jennifer, Xu, Gaixia, Prasad, Paras N., Schwartz, Stanley A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826119/
https://ncbi.nlm.nih.gov/pubmed/18329007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.01.093
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