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A Novel p40-Independent Function of IL-12p35 Is Required for Progression and Maintenance of Herpes Stromal Keratitis
PURPOSE. Interleukin (IL)-12p40 can couple with IL-12p35 or p19 chains to form the molecules IL-12p70 and IL-23, respectively, which promote T(H)1 cytokine responses. IL-12p35 can bind to EBI3 to form the anti-inflammatory molecule IL-35, but a proinflammatory function of IL-12p35 independent of IL-...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Association for Research in Vision and Ophthalmology, Inc.
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904011/ https://ncbi.nlm.nih.gov/pubmed/20207959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4368 |
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