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Identification of Novel Substrates for the Serine Protease HTRA1 in the Human RPE Secretome

PURPOSE. To define the role of the serine protease HTRA1 in age-related macular degeneration (AMD) by examining its expression level and identifying its potential substrates in the context of primary RPE cell extracellular milieu. METHODS. Primary RPE cell cultures were established from human donor...

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Autors principals: An, Eunkyung, Sen, Supti, Park, Sung Kyu, Gordish-Dressman, Heather, Hathout, Yetrib
Format: Artigo
Idioma:Inglês
Publicat: Association for Research in Vision and Ophthalmology, Inc. 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904004/
https://ncbi.nlm.nih.gov/pubmed/20207970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4853
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