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Identification of Novel Substrates for the Serine Protease HTRA1 in the Human RPE Secretome

PURPOSE. To define the role of the serine protease HTRA1 in age-related macular degeneration (AMD) by examining its expression level and identifying its potential substrates in the context of primary RPE cell extracellular milieu. METHODS. Primary RPE cell cultures were established from human donor...

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Bibliografiset tiedot
Päätekijät: An, Eunkyung, Sen, Supti, Park, Sung Kyu, Gordish-Dressman, Heather, Hathout, Yetrib
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Association for Research in Vision and Ophthalmology, Inc. 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904004/
https://ncbi.nlm.nih.gov/pubmed/20207970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4853
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