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Identification of Novel Substrates for the Serine Protease HTRA1 in the Human RPE Secretome

PURPOSE. To define the role of the serine protease HTRA1 in age-related macular degeneration (AMD) by examining its expression level and identifying its potential substrates in the context of primary RPE cell extracellular milieu. METHODS. Primary RPE cell cultures were established from human donor...

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Библиографические подробности
Главные авторы: An, Eunkyung, Sen, Supti, Park, Sung Kyu, Gordish-Dressman, Heather, Hathout, Yetrib
Формат: Artigo
Язык:Inglês
Опубликовано: Association for Research in Vision and Ophthalmology, Inc. 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904004/
https://ncbi.nlm.nih.gov/pubmed/20207970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4853
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