Susceptibility to Diet-Induced Hepatic Steatosis and Glucocorticoid Resistance in FK506-Binding Protein 52-Deficient Mice

Although FK506-binding protein 52 (FKBP52) is an established positive regulator of glucocorticoid receptor (GR) activity, an in vivo role for FKBP52 in glucocorticoid control of metabolism has not been reported. To address this question, FKBP52(+/−) mice were placed on a high-fat (HF) diet known to...

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Main Authors: Warrier, Manya, Hinds, Terry D., Ledford, Kelly J., Cash, Harrison A., Patel, Payal R., Bowman, Thomas A., Stechschulte, Lance A., Yong, Weidong, Shou, Weinian, Najjar, Sonia M., Sanchez, Edwin R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903936/
https://ncbi.nlm.nih.gov/pubmed/20427484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-1158
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