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Farnesoid X Receptor Activation Mediates Head-to-Tail Chromatin Looping in the Nr0b2 Gene Encoding Small Heterodimer Partner

As a unique nuclear receptor with only ligand-binding but no DNA-binding domain, small heterodimer partner (SHP) interacts with many transcription factors to inhibit their function. However, the regulation of SHP expression is not well understood. SHP is highly expressed in the liver, and previous s...

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Autori principali: Li, Guodong, Thomas, Ann M., Hart, Steven N., Zhong, Xiaobo, Wu, Dequan, Guo, Grace L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Endocrine Society 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903909/
https://ncbi.nlm.nih.gov/pubmed/20444884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0014
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