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ATP-independent glucose stimulation of sphingosine kinase in rat pancreatic islets
Sphingosine kinase (SPHK) catalyzes sphingosine 1-phosphate production, promoting cell survival and reducing apoptosis in isolated rat pancreatic islets. Glucose, the primary islet β-cell growth factor and insulin secretagogue, increased islet SPHK activity by 3- to 5-fold following acute (1 h) or p...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903817/ https://ncbi.nlm.nih.gov/pubmed/20371493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M000802 |
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