Gene Expression Profiles of Beta-Cell Enriched Tissue Obtained by Laser Capture Microdissection from Subjects with Type 2 Diabetes

BACKGROUND: Changes in gene expression in pancreatic beta-cells from type 2 diabetes (T2D) should provide insights into their abnormal insulin secretion and turnover. METHODOLOGY/PRINCIPAL FINDINGS: Frozen sections were obtained from cadaver pancreases of 10 control and 10 T2D human subjects. Beta-c...

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Bibliografiske detaljer
Main Authors: Marselli, Lorella, Thorne, Jeffrey, Dahiya, Sonika, Sgroi, Dennis C., Sharma, Arun, Bonner-Weir, Susan, Marchetti, Piero, Weir, Gordon C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903480/
https://ncbi.nlm.nih.gov/pubmed/20644627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011499
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