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The Role of Bcl-x(L) Protein in Nucleotide Excision Repair–Facilitated Cell Protection Against Cisplatin-Induced Apoptosis

Many anticancer drugs target the genomic DNA of cancer cells by generating DNA damage and inducing apoptosis. DNA repair protects cells against DNA damage–induced apoptosis. Although the mechanisms of DNA repair and apoptosis have been extensively studied, the mechanism by which DNA repair prevents...

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Detalhes bibliográficos
Main Authors: Lomonaco, Stephanie L., Xu, Xiaoxin S., Wang, Gan
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903458/
https://ncbi.nlm.nih.gov/pubmed/19317621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2008.0815
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