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CLOCK Regulates Circadian Rhythms of Hepatic Glycogen Synthesis through Transcriptional Activation of Gys2

Hepatic glycogen content is important for glucose homeostasis and exhibits robust circadian rhythms that peak at the end of the active phase in mammals. The activities of the rate-limiting enzymes for glycogenesis and glycogenolysis also show circadian rhythms, and the balance between them forms the...

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Detalhes bibliográficos
Main Authors: Doi, Ryosuke, Oishi, Katsutaka, Ishida, Norio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903367/
https://ncbi.nlm.nih.gov/pubmed/20430893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.110361
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