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Two Modes of β-Receptor Recognition Are Mediated by Distinct Epitopes on Mouse and Human Interleukin-3

The cytokine interleukin-3 (IL-3) is a critical regulator of inflammation and immune responses in mammals. IL-3 exerts its effects on target cells via receptors comprising an IL-3-specific α-subunit and common β-subunit (βc; shared with IL-5 and granulocyte-macrophage colony-stimulating factor) or a...

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Detalhes bibliográficos
Main Authors: Mirza, Shamaruh, Chen, Jinglong, Wen, Bin, Ewens, Cameron L., Dai, Jin, Murphy, James M., Young, Ian G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903361/
https://ncbi.nlm.nih.gov/pubmed/20472554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.117465
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