Protein Kinase A Phosphorylation Activates Vpr-Induced Cell Cycle Arrest during Human Immunodeficiency Virus Type 1 Infection

Infection with human immunodeficiency virus type 1 (HIV-1) causes an inexorable depletion of CD4(+) T cells. The loss of these cells is particularly pronounced in the mucosal immune system during acute infection, and the data suggest that direct viral cytopathicity is a major factor. Cell cycle arre...

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Bibliografiska uppgifter
Huvudupphovsmän: Barnitz, R. Anthony, Wan, Fengyi, Tripuraneni, Vinay, Bolton, Diane L., Lenardo, Michael J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2010
Ämnen:
Virus-Cell Interactions
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903295/
https://ncbi.nlm.nih.gov/pubmed/20392842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02273-09
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