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Vpr Cytopathicity Independent of G(2)/M Cell Cycle Arrest in Human Immunodeficiency Virus Type 1-Infected CD4(+) T Cells
The mechanism of CD4(+) T-cell depletion in human immunodeficiency virus type 1 (HIV-1)-infected individuals remains unknown, although mounting evidence suggests that direct viral cytopathicity contributes to this loss. The HIV-1 Vpr accessory protein causes cell death and arrests cells in the G(2)/...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1951439/ https://ncbi.nlm.nih.gov/pubmed/17553871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00122-07 |
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