Delineation of the Preferences and Requirements of the Human Immunodeficiency Virus Type 1 Dimerization Initiation Signal by Using an In Vivo Cell-Based Selection Approach

HIV-1 packages two copies of RNA into one particle, and the dimerization initiation signal (DIS) in the viral RNA plays an important role in selecting the copackaged RNA partner. We analyzed the DIS sequences of the circulating HIV-1 isolates in the GenBank database and observed that, in addition to...

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Bibliographic Details
Main Authors: Hussein, Islam T. M., Ni, Na, Galli, Andrea, Chen, Jianbo, Moore, Michael D., Hu, Wei-Shau
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903283/
https://ncbi.nlm.nih.gov/pubmed/20410279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01930-09
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