PREVALENCE OF COMBINATORIAL CYP2C9 AND VKORC1 GENOTYPES IN PUERTO RICANS: IMPLICATIONS FOR WARFARIN MANAGEMENT IN HISPANICS

Polymorphisms in the cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase complex subunit 1 (VKORC1) genes significantly alter the effective warfarin dose. We determined the frequencies of alleles, single carriers, and double carriers of single nucleotide polymorphisms (SNPs) in the CYP2C9 a...

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Main Authors: Duconge, Jorge, Cadilla, Carmen L., Windemuth, Andreas, Kocherla, Mohan, Gorowski, Krystyna, Seip, Richard L., Bogaard, Kali, Renta, Jessica Y., Piovanetti, Paola, D’Agostino, Darrin, Santiago-Borrero, Pedro J., Ruaño, Gualberto
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903231/
https://ncbi.nlm.nih.gov/pubmed/20073138
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