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Implementing genotype-guided antithrombotic therapy

Genotyping has the potential to improve the efficacy and safety of major antithrombotic drugs. For warfarin, the stable maintenance dose varies from 1–10 mg/day. The VKORC1 −1639G>A allele and the CYP2C9*2 and *3 alleles (cumulative frequency: 90% in Asians, 65% in Europeans and 20% in Africans),...

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Bibliografische gegevens
Hoofdauteurs: Seip, Richard L, Duconge, Jorge, Ruaño, Gualberto
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903229/
https://ncbi.nlm.nih.gov/pubmed/20462345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fca.10.6
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