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Boosting power for clinical trials using classifiers based on multiple biomarkers

Machine learning methods pool diverse information to perform computer-assisted diagnosis and predict future clinical decline. Here we introduce a machine learning method to boost power in clinical trials. We created a Support Vector Machine algorithm that combines brain imaging and other biomarkers...

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Main Authors: Kohannim, Omid, Hua, Xue, Hibar, Derrek P., Lee, Suh, Chou, Yi-Yu, Toga, Arthur W., Jack, Clifford R., Weiner, Michael W., Thompson, Paul M.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903199/
https://ncbi.nlm.nih.gov/pubmed/20541286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2010.04.022
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