Multilocus genetic profiling to empower drug trials and predict brain atrophy()

Designers of clinical trials for Alzheimer's disease (AD) and mild cognitive impairment (MCI) are actively considering structural and functional neuroimaging, cerebrospinal fluid and genetic biomarkers to reduce the sample sizes needed to detect therapeutic effects. Genetic pre-selection, howev...

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Detalhes bibliográficos
Main Authors: Kohannim, Omid, Hua, Xue, Rajagopalan, Priya, Hibar, Derrek P., Jahanshad, Neda, Grill, Joshua D., Apostolova, Liana G., Toga, Arthur W., Jack, Clifford R., Weiner, Michael W., Thompson, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777716/
https://ncbi.nlm.nih.gov/pubmed/24179834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2013.05.007
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