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Multilocus genetic profiling to empower drug trials and predict brain atrophy()
Designers of clinical trials for Alzheimer's disease (AD) and mild cognitive impairment (MCI) are actively considering structural and functional neuroimaging, cerebrospinal fluid and genetic biomarkers to reduce the sample sizes needed to detect therapeutic effects. Genetic pre-selection, howev...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3777716/ https://ncbi.nlm.nih.gov/pubmed/24179834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2013.05.007 |
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