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Syntheses of carbocyclic aminonucleosides and (−)-epi-4′-carbocyclic puromycin: Application of palladium(0)/indium iodide-allylations and tethered aminohydroxylations

Carbocyclic aminonucleosides and epi-4′-carbocyclic puromycin were prepared from an acylnitroso-derived hetero Diels–Alder cycloadduct. Pd(0)/InI-mediated allylations of a formyl species were used to install the 4′-hydroxymethyl group. A tethered aminohydroxylation strategy was employed to install t...

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Detalhes bibliográficos
Main Authors: Cesario, Cara, Tardibono, Lawrence P., Miller, Marvin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903068/
https://ncbi.nlm.nih.gov/pubmed/20640052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2010.04.006
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