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N-Acetyl-Cysteine Protects Against DNA Damage Associated with Lead Toxicity in HepG(2) Cells

Lead toxicity has been associated with its ability to interact and damage DNA. However, its molecular mechanisms of action are not fully understood. In vitro studies in our laboratory indicated that lead nitrate (PbNO(3)) induces cytotoxicity and oxidative stress to human liver carcinoma (HepG(2)) c...

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Bibliografiske detaljer
Main Authors: Yedjou, Clement G., Tchounwou, Christine K., Haile, Samuel, Edwards, Falicia, Tchounwou, Paul B.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902977/
https://ncbi.nlm.nih.gov/pubmed/20521395
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