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Spatial patterning of metabolism by mitochondria, oxygen and energy sinks in a model cytoplasm

Metabolite gradients may guide mitochondrial localization in cells, and angiogenesis in tissues [1, 2]. It is unclear if they can exist in single cells, because the length scale of most cells is small compared to expected diffusion times of metabolites. To investigate metabolic gradients, we need ex...

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Autori principali: Niethammer, Philipp, Kueh, Hao Yuan, Mitchison, Timothy
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902971/
https://ncbi.nlm.nih.gov/pubmed/18406136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.03.038
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