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Spatial patterning of metabolism by mitochondria, oxygen and energy sinks in a model cytoplasm

Metabolite gradients may guide mitochondrial localization in cells, and angiogenesis in tissues [1, 2]. It is unclear if they can exist in single cells, because the length scale of most cells is small compared to expected diffusion times of metabolites. To investigate metabolic gradients, we need ex...

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Detalhes bibliográficos
Main Authors: Niethammer, Philipp, Kueh, Hao Yuan, Mitchison, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902971/
https://ncbi.nlm.nih.gov/pubmed/18406136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.03.038
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