Patient-derived Granulocyte/Macrophage Colony–Stimulating Factor Autoantibodies Reproduce Pulmonary Alveolar Proteinosis in Nonhuman Primates

Rationale: Granulocyte/macrophage colony–stimulating factor (GM-CSF) autoantibodies (GMAb) are strongly associated with idiopathic pulmonary alveolar proteinosis (PAP) and are believed to be important in its pathogenesis. However, levels of GMAb do not correlate with disease severity and GMAb are al...

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Detalhes bibliográficos
Principais autores: Sakagami, Takuro, Beck, David, Uchida, Kanji, Suzuki, Takuji, Carey, Brenna C., Nakata, Koh, Keller, Gary, Wood, Robert E., Wert, Susan E., Ikegami, Machiko, Whitsett, Jeffrey A., Luisetti, Maurizio, Davies, Stella, Krischer, Jeffrey P., Brody, Alan, Ryckman, Fred, Trapnell, Bruce C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2010
Assuntos:
C. Critical Care
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902758/
https://ncbi.nlm.nih.gov/pubmed/20224064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201001-0008OC
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