Patient-derived Granulocyte/Macrophage Colony–Stimulating Factor Autoantibodies Reproduce Pulmonary Alveolar Proteinosis in Nonhuman Primates

Rationale: Granulocyte/macrophage colony–stimulating factor (GM-CSF) autoantibodies (GMAb) are strongly associated with idiopathic pulmonary alveolar proteinosis (PAP) and are believed to be important in its pathogenesis. However, levels of GMAb do not correlate with disease severity and GMAb are al...

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Главные авторы: Sakagami, Takuro, Beck, David, Uchida, Kanji, Suzuki, Takuji, Carey, Brenna C., Nakata, Koh, Keller, Gary, Wood, Robert E., Wert, Susan E., Ikegami, Machiko, Whitsett, Jeffrey A., Luisetti, Maurizio, Davies, Stella, Krischer, Jeffrey P., Brody, Alan, Ryckman, Fred, Trapnell, Bruce C.
Формат: Artigo
Язык:Inglês
Опубликовано: American Thoracic Society 2010
Предметы:
C. Critical Care
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902758/
https://ncbi.nlm.nih.gov/pubmed/20224064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201001-0008OC
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