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Hsp90 as a Gatekeeper of Tumor Angiogenesis: Clinical Promise and Potential Pitfalls

Tumor vascularization is an essential modulator of early tumor growth, progression, and therapeutic outcome. Although antiangiogenic treatments appear promising, intrinsic and acquired tumor resistance contributes to treatment failure. Clinical inhibition of the molecular chaperone heat shock protei...

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Autors principals: Bohonowych, J. E., Gopal, U., Isaacs, J. S.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902748/
https://ncbi.nlm.nih.gov/pubmed/20628489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/412985
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