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VEGF Induces More Severe Cerebrovascular Dysplasia in Eng(+/−) than in Alk1(+/−) Mice

Brain arteriovenous malformations (BAVMs) are an important cause of intracranial hemorrhage (ICH) in young adults. A small percent of BAVMs is due to hereditary hemorrhagic telangiectasia 1 and 2 (HHT1 and 2), which are caused by mutations in two genes involved in transforming growth factor-β signal...

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Detalhes bibliográficos
Main Authors: Hao, Qi, Zhu, Yiqian, Su, Hua, Shen, Fanxia, Yang, Guo-Yuan, Kim, Helen, Young, William L.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902730/
https://ncbi.nlm.nih.gov/pubmed/20640035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-010-0020-x
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