Induction of cytotoxic T lymphocytes primed with Tumor RNA-loaded Dendritic Cells in esophageal squamous cell carcinoma: preliminary step for DC vaccine design

BACKGROUND: Dendritic Cells (DC) are potent antigen presenting cells with the ability to prime naïve T cells and convert them to cytotoxic T-lymphocytes (CTL). We evaluated the capability of autologous DCs transfected with total tumor and normal RNA to induce cytotoxic CTL as the preliminary step to...

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Bibliographic Details
Main Authors: Gholamin, Mehran, Moaven, Omeed, Farshchian, Moein, Mahmoudi, Mahmoud, Sankian, Mojtaba, Memar, Bahram, Forghani, Mohammad Naser, Malekzadeh, Reza, Rajabi-Mashhadi, Mohammad Taghi, Abbaszadegan, Mohammad Reza
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902443/
https://ncbi.nlm.nih.gov/pubmed/20525404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-261
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