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Recessive multiple epiphyseal dysplasia (rMED) with homozygosity for C653S mutation in the DTDST gene - Phenotype, molecular diagnosis and surgical treatment of habitual dislocation of multilayered patella: Case report

BACKGROUND: Multiple epiphyseal dysplasia (MED) is one of the more common generalised skeletal dysplasias. Due to its clinical heterogeneity diagnosis may be difficult. Mutations of at least six separate genes can cause MED. Joint deformities, joint pain and gait disorders are common symptoms. CASE...

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Detalhes bibliográficos
Main Authors: Hinrichs, Timo, Superti-Furga, Andrea, Scheiderer, Wolf-Dieter, Bonafé, Luisa, Brenner, Rolf E, Mattes, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902411/
https://ncbi.nlm.nih.gov/pubmed/20525296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-11-110
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