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In vivo transgene expression from an adenoviral vector is altered following a 6-OHDA lesion of the dopamine system

We have investigated the in vivo dynamics of an adenovirus-based, LacZ expressing vector, RAd36, at different doses, when injected unilaterally into the corpus striatum of normal rats. We have further investigated the characteristics of this vector in the presence of a 6-OHDA lesion of the nigrostri...

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Hlavní autoři: Torres, E.M., Monville, C., Lowenstein, P.R., Castro, M.G., Dunnett, S.B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902248/
https://ncbi.nlm.nih.gov/pubmed/15950755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbrainres.2004.10.046
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