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Can robots patch-clamp as well as humans? Characterization of a novel sodium channel mutation

Ion channel missense mutations cause disorders of excitability by changing channel biophysical properties. As an increasing number of new naturally occurring mutations have been identified, and the number of other mutations produced by molecular approaches such as in situ mutagenesis has increased,...

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Detalhes bibliográficos
Main Authors: Estacion, M, Choi, J S, Eastman, E M, Lin, Z, Li, Y, Tyrrell, L, Yang, Y, Dib-Hajj, S D, Waxman, S G
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901980/
https://ncbi.nlm.nih.gov/pubmed/20123784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.186114
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