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Current Hypotheses on How Microsatellite Instability Leads to Enhanced Survival of Lynch Syndrome Patients

High levels of microsatellite instability (MSI-high) are a cardinal feature of colorectal tumors from patients with Lynch Syndrome. Other key characteristics of Lynch Syndrome are that these patients experience fewer metastases and have enhanced survival when compared to patients diagnosed with micr...

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Autors principals: Drescher, Kristen M., Sharma, Poonam, Lynch, Henry T.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901607/
https://ncbi.nlm.nih.gov/pubmed/20631828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/170432
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