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Current Hypotheses on How Microsatellite Instability Leads to Enhanced Survival of Lynch Syndrome Patients

High levels of microsatellite instability (MSI-high) are a cardinal feature of colorectal tumors from patients with Lynch Syndrome. Other key characteristics of Lynch Syndrome are that these patients experience fewer metastases and have enhanced survival when compared to patients diagnosed with micr...

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Detalhes bibliográficos
Main Authors: Drescher, Kristen M., Sharma, Poonam, Lynch, Henry T.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901607/
https://ncbi.nlm.nih.gov/pubmed/20631828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/170432
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