Evidence that TGFA influences risk to cleft lip with/without cleft palate through unconventional genetic mechanisms

This study examined the association between markers in transforming growth factor alpha (TGFA) and isolated, non-syndromic cleft lip with/without palate (CL/P) using a case–parent trio design, considering parent-of-origin effects. We also tested for gene–environmental interaction with common materna...

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Autors principals: Sull, Jae Woong, Liang, Kung-Yee, Hetmanski, Jacqueline B., Wu, Tao, Fallin, Margaret Daniele, Ingersoll, Roxann G., Park, Ji Wan, Wu-Chou, Yah-Huei, Chen, Philip K., Chong, Samuel S., Cheah, Felicia, Yeow, Vincent, Park, Beyoung Yun, Jee, Sun Ha, Jabs, Ethylin Wang, Redett, Richard, Scott, Alan F., Beaty, Terri H.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901599/
https://ncbi.nlm.nih.gov/pubmed/19444471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-009-0680-3
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