Evidence of gene–environment interaction for the IRF6 gene and maternal multivitamin supplementation in controlling the risk of cleft lip with/without cleft palate

Although multiple genes have been identified as genetic risk factors for isolated, non-syndromic cleft lip with/without cleft palate (CL/P), a complex and heterogeneous birth defect, interferon regulatory factor 6 gene (IRF6) is one of the best documented genetic risk factors. In this study, we test...

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Main Authors: Wu, Tao, Liang, Kung Yee, Hetmanski, Jacqueline B., Ruczinski, Ingo, Fallin, Margaret Daniele, Ingersoll, Roxann G., Wang, Hong, Huang, Shangzhi, Ye, Xiaoqian, Wu-Chou, Yah-Huei, Chen, Philip K., Jabs, Ethylin W., Shi, Bing, Redett, Richard, Scott, Alan F., Beaty, Terri H.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956506/
https://ncbi.nlm.nih.gov/pubmed/20652317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-010-0863-y
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