Energetic Effects for Observed and Unobserved HIV-1 Reverse Transcriptase Mutations of Residues L100, V106 and Y181 in the Presence of Nevirapine and Efavirenz

The effect of mutations on amino acid residues L100, V106, and Y181 for unbound HIV-1 reverse transcriptase (RT) and RT bound to nevirapine and efavirenz was investigated using Monte Carlo/Free Energy Perturbation calculations. Using both native and bound crystal structures of RT, mutation of the am...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Smith, Marilyn B. Kroeger, Rader, Lenea H., Franklin, Amanda M., Taylor, Emily V., Smith, Katie D., Smith, Richard H., Tirado-Rives, Julian, Jorgensen, William L.
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901594/
https://ncbi.nlm.nih.gov/pubmed/18166457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.12.033
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars