A Pathologic Cascade Leading to Synaptic Dysfunction in α-Synuclein-Induced Neurodegeneration

Several neurodegenerative diseases are typified by intraneuronal α-synuclein deposits, synaptic dysfunction, and dementia. While even modest α-synuclein elevations can be pathologic, the precise cascade of events induced by excessive α-synuclein and eventually culminating in synaptotoxicity is uncle...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Scott, David A., Tabarean, Iustin, Tang, Yong, Cartier, Anna, Masliah, Eliezer, Roy, Subhojit
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2010
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901533/
https://ncbi.nlm.nih.gov/pubmed/20554859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1091-10.2010
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