Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression

B-cell chronic lymphocytic leukemia (B-CLL), the most common leukemia in the Western world, occurs in two forms, aggressive (showing for the most part high ZAP-70 expression and unmutated IgH V(H)) and indolent (showing low ZAP-70 expression and mutated IgH V(H)). We found that miR-29a is up-regulat...

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Autors principals: Santanam, Urmila, Zanesi, Nicola, Efanov, Alexey, Costinean, Stefan, Palamarchuk, Alexey, Hagan, John P., Volinia, Stefano, Alder, Hansjuerg, Rassenti, Laura, Kipps, Thomas, Croce, Carlo M., Pekarsky, Yuri
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901490/
https://ncbi.nlm.nih.gov/pubmed/20566844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007186107
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