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Control of transient, resurgent, and persistent current by open-channel block by Na channel β4 in cultured cerebellar granule neurons

Voltage-gated Na channels in several classes of neurons, including cells of the cerebellum, are subject to an open-channel block and unblock by an endogenous protein. The Na(V)β4 (Scn4b) subunit is a candidate blocking protein because a free peptide from its cytoplasmic tail, the β4 peptide, can blo...

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Bibliographic Details
Main Authors: Bant, Jason S., Raman, Indira M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901465/
https://ncbi.nlm.nih.gov/pubmed/20566860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005633107
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