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Kinesin-1 heavy chain mediates microtubule sliding to drive changes in cell shape
Microtubules are typically observed to buckle and loop during interphase in cultured cells by an unknown mechanism. We show that lateral microtubule movement and looping is a result of microtubules sliding against one another in interphase Drosophila S2 cells. RNAi of the kinesin-1 heavy chain (KHC)...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2901438/ https://ncbi.nlm.nih.gov/pubmed/20566873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004736107 |
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