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Kinesin-1 heavy chain mediates microtubule sliding to drive changes in cell shape

Microtubules are typically observed to buckle and loop during interphase in cultured cells by an unknown mechanism. We show that lateral microtubule movement and looping is a result of microtubules sliding against one another in interphase Drosophila S2 cells. RNAi of the kinesin-1 heavy chain (KHC)...

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書誌詳細
主要な著者: Jolly, Amber L., Kim, Hwajin, Srinivasan, Divya, Lakonishok, Margot, Larson, Adam G., Gelfand, Vladimir I.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2010
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901438/
https://ncbi.nlm.nih.gov/pubmed/20566873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004736107
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